Published 1994
| Version v1
Publication
5-Substituted 4-Isoxazoleacetic acids with analgesic activity.
Contributors
Description
The synthesis of some 5-substituted 4-isoxazoleacetic acids starting from 5-substituted 4-isoxazolemethanols via their conversion to 4-(bromomethyl)isoxazoles, 4-isoxazoleacetonitriles and acid hydrolysis of the latter is described. 5-Ethyl- and 5-propyl-4-isoxazoleacetic acids showed in the writhing test an analgesic activity comparable to that of aspirin.
Additional details
Identifiers
- URL
- http://hdl.handle.net/11567/381916
- URN
- urn:oai:iris.unige.it:11567/381916
Origin repository
- Origin repository
- UNIGE