Published 2001
| Version v1
Publication
Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
Description
Macrophage activation syndrome (MAS) is a potentially life threatening complication of chronic rheumatic diseases, particularly systemic juvenile idiopathic arthritis (JIA). A number of triggers have been related to the development of MAS, including viral infections, nonsteroidal antiinflammatory drug therapy, and gold salt injections. We describe a patient with systemic JIA who developed MAS shortly after receiving methotrexate, suggesting that this drug can be regarded as a potential trigger of MAS in children with JIA.
Additional details
- URL
- http://hdl.handle.net/11567/276462
- URN
- urn:oai:iris.unige.it:11567/276462
- Origin repository
- UNIGE