Published August 2006
| Version v1
Journal article
The Inflammatory C-Reactive Protein Is Increased in Both Liver and Adipose Tissue in Severely Obese Patients Independently from Metabolic Syndrome, Type 2 Diabetes, and NASH
Contributors
Others:
- Centre méditerranéen de médecine moléculaire (C3M) ; Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA)
- Centre Hospitalier Universitaire de Nice (CHU Nice)
- Hôpital Archet 2 [Nice] (CHU)
- Université de Rouen Normandie (UNIROUEN) ; Normandie Université (NU)
- Matière et Systèmes Complexes (MSC) ; Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)
- Service d'Anatomie et Cytologie Pathologiques ; Hôpital Pasteur [Nice] (CHU)
- Ecole Polytechnice Universitaire de Nice (EPU Nice -Polytech'Nice-Sophia) ; Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Université Côte d'Azur (UniCA)
- Pôle Digestif ; Centre Hospitalier Universitaire de Nice (CHU Nice)-Hôpital l'Archet
- Service de Chirurgie Digestive / Centre de Transplantation Hépatique [CHU Nice] ; Centre Hospitalier Universitaire de Nice (CHU Nice)
- Signalisation moléculaire et obésité ; Université Nice Sophia Antipolis (1965 - 2019) (UNS)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM)
Description
C-Reactive Protein (CRP), a nonspecific marker of inflammation that is moderately elevated in obesity, metabolic syndrome (MS), and type 2 diabetes, has been proposed as a surrogate marker of nonalcoholic steatohepatitis (NASH). Its clinical usefulness in the diagnosis of NASH was evaluated in severely obese patients without or with MS, diabetes, and NASH and the potential roles of the liver and of the adipose tissue in CRP production were characterized.
Abstract
International audienceAdditional details
Identifiers
- URL
- https://hal.science/hal-04496806
- URN
- urn:oai:HAL:hal-04496806v1
Origin repository
- Origin repository
- UNICA