Towards a P Systems Pseudomonas Quorum Sensing Model

Description

Pseudomonas aeruginosa is an opportunistic bacterium that exploits quorum sensing communication to synchronize individuals in a colony and this leads to an increase in the effectiveness of its virulence. In this paper we derived a mechanistic P systems model to describe the behavior of a single bacterium and we discuss a possible approach, based on an evolutionary algorithm, to tune its parameters that will allow a quantitative simulation of the system.

Abstract

Kingdom's Engineering and Physical Sciences Research Council EP/D021847/1

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