Published 1992
| Version v1
Publication
4-Substituted 1-methyl-1H-indazoles with analgesic, antiinflammatory and antipyretic activities
Description
The synthesis of [(1-methyl-1H-indazol-4-yl)oxy]acetic acid 4, 1-methyl-1H-indazole-4-acetic acid 9, 2-(1-methyl-1H-indazol-4-yl)propanoic acid 15 and [[(1,5,6,7-tetrahydro-1-methyl-4H-indazol-4-ylidene)amino]oxy]acet ic acid 16, as well as of amides and esters derived from 4 and 9, starting from 1,5,6,7-tetrahydro-1-methyl-4H-indazol-4-one is described. Some of the above compounds showed weak antiinflammatory, analgesic, antipyretic and hypotensive activities in rats and mice, as well as moderate platelet antiaggregating effects in vitro.
Additional details
Identifiers
- URL
- http://hdl.handle.net/11567/294547
- URN
- urn:oai:iris.unige.it:11567/294547
Origin repository
- Origin repository
- UNIGE