Published 2005
| Version v1
Publication
In vivo and in vitro exposures of carps to graded concentrations of endocrine disrupting chemicals
Description
The objective of this study was to correlate morphological and biochemical
parameters of reproductive activity in fish exposed to graded concentrations
of endocrine disrupting chemicals. Two-year-old carps were exposed
for two weeks to graded concentrations of ethynyl-estradiol, tamoxifen, and
flutamide. For each chemical, morphological alterations of the gonads and liver
were described according to biomarker and sex steroid levels. In parallel, isolated
follicular cells (FCs) and testis fragments were incubated in the presence
or absence of carp pituitary homogenate and 25-hydroxycholesterol. Media
were analyzed for sex steroid level evaluations.
Additional details
Identifiers
- URL
- http://hdl.handle.net/11567/210543
- URN
- urn:oai:iris.unige.it:11567/210543
Origin repository
- Origin repository
- UNIGE