Revised upper limb module for spinal muscular atrophy: 12 month changes
- Others:
- Pera, M. C.
- Coratti, G.
- Mazzone, E. S.
- Montes, J.
- Scoto, M.
- De Sanctis, R.
- Main, M.
- Mayhew, A.
- Muni Lofra, R.
- Dunaway Young, S.
- Glanzman, A. M.
- Duong, T.
- Pasternak, A.
- Ramsey, D.
- Darras, B.
- Day, J. W.
- Finkel, R. S.
- De Vivo, D. C.
- Sormani, M. P.
- Bovis, F.
- Straub, V.
- Muntoni, F.
- Pane, M.
- Mercuri, E.
Description
Introduction: The aim of the study was to assess 12 month changes in upper limb function in patients affected by spinal muscular atrophy type 2 and 3. Methods: Longitudinal 12 month data was collected in 114 patients, 60 type 2 and 54 type 3, using the Revised Upper Limb Module. Results: The 12 month changes ranged between -7 and 9 (mean: -0.41; SD: 2.93). The mean changes were not significantly different between the three spinal muscular atrophy groups (-0.45 in type 2, -0.23 in non-ambulant type 3 and -0.34 in ambulant type 3, p = 0.96) and the relationship between 12 month change and age classes was not significantly different among the three types of SMA patients. Discussion: Our results confirm that the Module explores a wide range of functional abilities and can be used in ambulant and non-ambulant patients of different ages in conjunction with other functional scales. Muscle Nerve 59:426–430, 2019.
Additional details
- URL
- http://hdl.handle.net/11567/946874
- URN
- urn:oai:iris.unige.it:11567/946874
- Origin repository
- UNIGE