Published February 2018
| Version v1
Journal article
Decoding glycan recognition by bacterial toxins
- Creators
- Bourdoulous, Sandrine
- Lemichez, Emmanuel
- Others:
- Institut Cochin (IC UM3 (UMR 8104 / U1016)) ; Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
- Toxines bactériennes dans la relation hôtes-pathogènes ; Université Nice Sophia Antipolis (1965 - 2019) (UNS) ; COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)
Description
Functional and structural studies highlight the remarkable evolution and features of the typhoid toxin from Salmonella Typhi. This reveals that attachment of the toxin to specific N-glycan chains accounts for its tropism for selected human tissues.
Abstract
Comment on : In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor. [Nat Microbiol. 2018]
Abstract
International audience
Additional details
- URL
- https://hal-pasteur.archives-ouvertes.fr/pasteur-02448664
- URN
- urn:oai:HAL:pasteur-02448664v1
- Origin repository
- UNICA