Published 2012
| Version v1
Publication
An Original Route to Newly-Functionalized Indoles and Carbazoles Starting from the Ring-Opening of Nitrothiophenes
Citation
APA
Description
The multifaceted behavior of nitrobutadienes deriving from the initial ring-opening of nitrothiophenes finds a further clear-cut example in their Michael-type acceptor reactivity towards indole. Thus, depending on the starting diene, either newly-functionalized indoles or carbazoles are produced, the latter as the result of an appealing double (intermolecular + intramolecular) Michael-type addition to a nitrovinylic moiety. The outcome encompasses motifs for both mechanistic and synthetic interest in the field of heterocycles endowed with possible pharmacological activity.
Additional details
- URL
- http://hdl.handle.net/11567/299193
- URN
- urn:oai:iris.unige.it:11567/299193
- Origin repository
- UNIGE