Development of a French Isometric Strength Normative Database for Adults Using Quantitative Muscle Testing

Creators: Hogrel, Jean-Yves; Payan, Christine A.; Ollivier, Gwenn; Tanant, Véronique; Attarian, Shahram; Couillandre, Annabelle; Dupeyron, Arnaud; Lacomblez, Lucette; Doppler, Valérie; Meininger, Vincent; Tranchant, Christine; Pouget, Jean; Desnuelle, Claude

Others:: Thérapie des maladies du muscle strié ; Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS); Hôpital de la Timone [CHU - APHM] (TIMONE); Centre de Recherche sur le Sport et le Mouvement (CeRSM) ; Université Paris Nanterre (UPN); Département de Rééducation et Réadaptation Neuro Orthopédique [Nîmes] (Pôle NACRRE) ; Hôpital Universitaire Carémeau [Nîmes] (CHU Nîmes) ; Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes); Euromov (EuroMov) ; Université de Montpellier (UM); Fédération des Maladies du Système Nerveux ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP] ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU); Service de Pharmacologie médicale [CHU Pitié-Salpêtrière] ; CHU Pitié-Salpêtrière [AP-HP] ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU); Département de Neurologie ; CHU Strasbourg-Hopital Civil; CHU Nice ; Université Nice Sophia Antipolis (1965 - 2019) (UNS) ; COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA); Université Nice Sophia Antipolis (1965 - 2019) (UNS) ; COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)

Description

OBJECTIVE: To establish a normative database for isometric strength measured by quantitative muscle testing (QMT) for a French adult population.DESIGN: Measurement of maximal voluntary isometric contraction.SETTING: Four clinical centers involved in neuromuscular disorders.PARTICIPANTS: A total of 315 healthy adults (147 men, 168 women) ages 20 to 80 years.INTERVENTIONS: Not applicable.MAIN OUTCOME MEASURE: Isometric torque values of 14 muscle functions (13 bilaterally and neck).RESULTS: This study led to the development of a French isometric strength normative database for adults measured by QMT. For each muscle function, predictive regression models using age, sex, and weight are proposed. Some methodologic issues concerning strength measurement are discussed.CONCLUSIONS: This database can be used to compute relative deficits in muscle strength for 27 muscle functions and also to estimate composite scores for follow-up of patients either during the natural history of their disease or during a therapeutic trial.

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Development of a French Isometric Strength Normative Database for Adults Using Quantitative Muscle Testing

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