Groupwise structural parcellation of the whole cortex: A logistic random effects model based approach
- Others:
- Computational Imaging of the Central Nervous System (ATHENA) ; Inria Sophia Antipolis - Méditerranée (CRISAM) ; Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)
- COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)
- Harvard Medical School [Boston] (HMS)
- European Project: 694665,H2020 ERC,ERC-2015-AdG,CoBCoM(2016)
Description
Current theories hold that brain function is highly related to long-range physical connections through axonal bundles, namely extrinsic connectivity However, obtaining a groupwise cortical parcellation based on extrinsic connectivity remains challenging. Current parcellation methods are computationally expensive; need tuning of several parameters or rely on ad-hoc constraints. Furthermore, none of these methods present a model for the cortical extrinsic connectivity of the cortex. To tackle these problems, we propose a parsimonious model for the extrinsic connectivity and an effcient parceling technique based on clustering of tractograms. Our technique allows the creation of single subject and groupwise parcellations of the whole cortex. The parcellations obtained with our technique are in agreement with structural and functional parcellations in the literature. In particular, the motor and sensory cortex are subdivided in agreement with the human homunculus of Pen eld. We illustrate this by comparing our resulting parcels with the motor strip mapping included in the Human Connectome Project data.
Abstract
International audience
Additional details
- URL
- https://hal.science/hal-01426625
- URN
- urn:oai:HAL:hal-01426625v1
- Origin repository
- UNICA