Published 2008 | Version v1
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Simple synthesis of P1P2-Diadenosine 5'-pyrophosphate

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Description

Pyrophosphate-linked coenzymes play essential roles in several biochemical systems. Symmetrical diadenosine-5'-pyrophosphate (Ap2A) has been synthesized from adenosine-5'-phosphate in virtually quantitative yield. The simple procedure is carried out in anhydrous pyridine using adenosine phosphoromorpholidate and adenosine monophosphate bis-(tri-n-butylammonium salt) as coupling reagents.

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URL
http://hdl.handle.net/11567/245787
URN
urn:oai:iris.unige.it:11567/245787

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UNIGE