Published July 19, 2024 | Version v1
Journal article

Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review

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Description

Fexofenadine is a second-generation inverse agonist of H1-receptor of histamine which is highly selective with proven efficacy in relieving symptoms associated with allergic conditions. It has an additional benefit of not penetrating the blood-brain barrier and therefore do not induce sedation and not impair the cognitive function/psychomotor performance. This review aimed at providing evidence based on available controlled studies to reinforce the non-sedative property of fexofenadine for treating patients with allergic rhinitis and urticaria.

Abstract

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Identifiers

URL
https://hal.science/hal-04920792
URN
urn:oai:HAL:hal-04920792v1

Origin repository

Origin repository
UNICA