Published July 12, 2022 | Version v1
Publication

Apolar carbohydrates as DNA capping agents

Description

Mono- and disaccharides have been shown to stack on top of DNA duplexes stabilizing sequences with terminal C–G base pairs. Here we present an apolar version of glucose and cellobiose as new capping agents that stack on DNA increasing considerably its stability with respect to their natural polyhydroxylated mono- and disaccharide DNA conjugates.

Abstract

Ministerio de Ciencia, Innovación y Universidades CTQ2006-01123, CTQ2007-68014- C02-02, CTQ2009-13705, BFU2007-63287

Abstract

Generalitat de Catalunya 2009/SGR/208

Abstract

Instituto de Salud Carlos III CB06_01_0019

Additional details

Created:
December 4, 2022
Modified:
November 28, 2023