Published June 6, 2016 | Version v1
Conference paper

Joint estimation of effective population size and selection coefficient without neutrel markers: method validation and application to experimental evolution of viruses

Contributors

Others:

Description

Experimental evolution studies deserve considerable attention to the estimation of basic evolutionary forces such as selection and genetic drift. With the advent of high-throughput sequencing techniques, these studies gained a renewed attention. However the joint estimation of selection and genetic drift still remain challenging when no neutral markers are available, a common situation with many microbes, such as viruses, due to their small tightly packed genomes.

Abstract

International audience

Additional details

Identifiers

URL
https://hal.inrae.fr/hal-02739698
URN
urn:oai:HAL:hal-02739698v1