Published January 2017 | Version v1
Journal article

Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer

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Description

The purpose of this study was to investigate the effects of combining the phosphotidylinositol-3-kinase (PI3K) inhibitor buparlisib (BKM)120 with the anti-epidermal growth factor receptor (EGFR) agent cetuximab and radiotherapy (RT) on an orthotopic model of head and neck squamous cell carcinoma (HNSCC).

Abstract

International audience

Additional details

Identifiers

URL
https://hal.science/hal-01675150
URN
urn:oai:HAL:hal-01675150v1

Origin repository

Origin repository
UNICA