CSF and serum IgG and albumin in schizophrenics

Description

CSF and serum concentrations of IgG and albumin were determined by single radial immunodiffusion in 25 schizophrenics, 22 endogenously depressed subjects and 37 controls. No significant difference of the mean values was found among the 3 groups but, considering the homogeneity of variance, IgG and albumin concentrations of CSF were distributed less homogeneously in the schizophrenics than in the other groups. This was attributed to the behaviour of a relatively small number of cases. The possible meaning of this finding are discussed, also taking into consideration the hitherto conflicting data from the literature.

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