Increased Stroke Risk in Patients with Parkinson's Disease with LRRK2 Mutations

Description

Parkinson's disease (PD) is associated with an increasedstroke risk, however, no relationship between coronary arterydisease (CAD) and PD was found.1To date, little is knownabout the influence of PD-related genes, such as the leucine-rich repeat kinase 2 (LRRK2), the parkin (PRKN) and theglucocerebrosidase (GBA) genes, in the vascular risk of thesepatients. This work aims to determine whether the vascularrisk differs between sporadic/familial PD forms and controls.

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