Phenotype modifications of T-cells and their shift toward a Th2 response in patients with systemic lupus erythematosus supplemented with different monthly regimens of vitamin D

Creators: Piantoni, S; Andreoli, L; SCARSI, MARCO; Zanola, A; Dall'Ara, F; PIZZORNI, CARMEN; CUTOLO, MAURIZIO; Airò, P; Tincani, A.

Others:: Piantoni, S; Andreoli, L; Scarsi, Marco; Zanola, A; Dall'Ara, F; Pizzorni, Carmen; Cutolo, Maurizio; Airò, P; Tincani, A.

Description

Vitamin D receptor is constitutively expressed on the lymphocyte surface. Recent studies highlight that vitamin D may exert actions on T-cells, inhibiting Th1 and Th17 response and enhancing Th2 and T-regulatory (T-reg) function.

Phenotype modifications of T-cells and their shift toward a Th2 response in patients with systemic lupus erythematosus supplemented with different monthly regimens of vitamin D

Description

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