ALCALDE HERRERO , Ana Isabel

The effect of BaCI2 on galactose transport across isolated rat small intestine has been investigated. The addition of 5 mM BaCI2 or theophylline (3 mM) to the bathing solutions increased .cell water free sugar accumulation and decreased mucosa! to serosa! sugar fluxcs. Howevcr the effects of BaCI2 werc smaller than those induced by...

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The effect of trifluoperazine and RMI 12330A on D-Galactose accumulation was studied in isolated rat intestinal mucosa. Both drugs inhibited the theophylline and phloretin-induced increase in tissue sugar accumulation in a concentration-dependent fashion, with IC50 values close to 10- 6 M. These findings suggest that calmodulin might mediate...