2002 (v1)
Publication
No description
Uploaded on: April 14, 2023
B
C
BOTTINO , Cristina
Last name: BOTTINO
First name: Cristina
Email: cristina.bottino@unige.it
Institution: UNIGE
Links
-
-
1989 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2002 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2001 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2000 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2000 (v1)Publication
No description
Uploaded on: April 14, 2023 -
1989 (v1)Publication
No description
Uploaded on: April 14, 2023 -
1988 (v1)Publication
No description
Uploaded on: March 31, 2023 -
2002 (v1)Publication
No description
Uploaded on: April 14, 2023 -
1999 (v1)Publication
No description
Uploaded on: December 5, 2022 -
2001 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2004 (v1)Publication
The co-signaling receptors specific for the different members of the B7 molecular family are cell surface glycoproteins that are essential to modulate and tune the TCR-mediated activation of T lymphocytes. The common characteristic is that their function appears to be dependent on the engagement of TCR by antigenic peptides presented in the MHC...
Uploaded on: March 27, 2023 -
2002 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2005 (v1)PublicationHuman natural killer cells: molecular mechanisms controlling NK cell activation and tumor cell lysis
Natural killer cells represent a highly specialized lymphoid population with a potent cytolytic activity against virus-infected or tumor cells. Their function is regulated by a series of inhibiting or activating signals. The mechanisms by which NK cells kill susceptible target cells was thought to be elucidated after the discovery of inhibitory...
Uploaded on: March 27, 2023 -
1988 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2004 (v1)Publication
After the discovery, in humans and mice, of inhibitory natural killer (NK) receptors specific for MHC class I molecules, the mechanism by which NK cells kill tumor or virus-infected cells was thought to be clarified: NK cells would kill those target cells that have lost, or underexpress, MHC class I molecules. However, a more complex scenario...
Uploaded on: March 27, 2023 -
1988 (v1)Publication
No description
Uploaded on: March 31, 2023 -
2003 (v1)Publication
The capability of killing various tumors or cells infected by certain viruses is a property shared by natural killer (NK) cells and by a subset of cytolytic T lymphocytes (CTLs) termed NK-CTL. Recent analysis of the molecular basis in these phenomena, however, revealed rather different molecular mechanisms. Thus, while NK cell cytotoxicity is...
Uploaded on: April 14, 2023 -
2006 (v1)Publication
The identification of MHC-class I-specific inhibitory receptors in humans and mice provided a first explanation of why NK cells can kill target cells that have lost or underexpress MHC-class I molecules but spare normal cells. However, the molecular basis of NK-mediated recognition and tumor cell killing revealed a higher degree of complexity....
Uploaded on: April 14, 2023 -
1996 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2003 (v1)Publication
No description
Uploaded on: March 25, 2023 -
2009 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2006 (v1)Publication
Natural killer (NK) cells have been known for many years as the lymphocyte subset characterized by the highest cytolytic potential against virus-infected and tumor-transformed cells. A surprisingly high number of surface molecules have been recognized that regulate human NK cell function. These include MHC-specific inhibitory receptors, which...
Uploaded on: March 31, 2023