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BEAULIEU , Jean-Martin

Last name: BEAULIEU

First name: Jean-Martin

April 2014 (v1)

Journal article

Metadata-only

Stimulation of 5-HT2C Receptors Improves Cognitive Deficits Induced by Human Tryptophan Hydroxylase 2 Loss of Function Mutation

Del'Guidice, Thomas Lemay, Francis Lemasson, Morgane

Polymorphisms in the gene encoding the serotonin synthesis enzyme Tph2 have been identified in mental illnesses, including bipolar disorder, major depression, autism, schizophrenia, and ADHD. Deficits in cognitive flexibility and perseverative behaviors are shared common symptoms in these disorders. However, little is known about the impact of...

Uploaded on: December 4, 2022
January 2014 (v1)

Journal article

Metadata-only

Dissociations between cognitive and motor effects of psychostimulants and atomoxetine in hyperactive DAT-KO mice

Del'Guidice, Thomas Lemasson, Morgane Etievant, Adeline

Psychostimulants such as amphetamine and methylphenidate, which target the dopamine transporter (DAT), are the most frequently used drugs for the treatment of hyperactivity and cognitive deficits in humans with attention deficit hyperactivity disorder (ADHD). While psychostimulants can increase activity in healthy subjects, they exert a...

Uploaded on: December 4, 2022