BELMIN , Joël

Background: It is not known if widespread vaccination can prevent the spread of SARS-CoV-2 in subpopulations at high risk, like older adults in nursing homes (NH).Objective: To know if COVID-19 outbreaks can occur in NH with high vaccination coverage among its residents. Methods: In this case series, we identified, using national professional...

Objectives - To analyze long-term cognitive status and function after cochlear implantation in profoundly deaf individuals. Design - Prospective observational longitudinal study. Setting - Ten academic medical centers referent for cochlear implantation. Participants - Individuals aged 65 and older who qualified for cochlear implantation...

INTRODUCTION:Diagnostic relevance of plasma amyloid β (Aβ) for Alzheimer's disease (AD) process yields conflicting results. The objective of the study was to assess plasma levels of Aβ42 and Aβ40 in amnestic mild cognitive impairment (MCI), nonamnestic MCI, and AD patients and to investigate relationships between peripheral and central...

INTRODUCTION: Blood-based biomarkers are the next challenge for Alzheimer's disease (AD) diagnosis and prognosis. METHODS: Mild cognitive impairment (MCI) participants (N = 485) of the BALTAZAR study, a large-scale longitudinal multicenter cohort, were followed-up for 3 years. A total of 165 of them converted to dementia (95% AD). Associations...