BILLON , Nathalie

The current epidemic of obesity and overweight has caused a surge of interest in the study of adipose tissue formation. Much progress has been made in defining the transcriptional networks controlling the terminal differentiation of adipocyte progenitors into mature adipocytes. However, the early steps of adipocyte development and the embryonic...

The current epidemic of obesity has caused a surge of interest in the study of adipose tissue formation. Much progress has been made in defining the transcriptional networks controlling the terminal differentiation of preadipocytes into mature adipocytes. However, the mechanisms that direct MSCs (mesenchymal stem cells) down the adipocyte...

C horoid plexus carcinomas (CPCs) are World Health Organization [WHO] grade III brain tumors predominantly found in children (1,2). Implementation of successful therapy for CPCs has been hampered by the lack of appropriate preclinical models. Here we review the Otx2 CreER/ +; Rosa MycT58A/MycT58A ; Trp 53fl/fl novel CPC mouse model we recently...