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BOURDEAUT , Franck

Last name: BOURDEAUT

First name: Franck

2022 (v1)

Publication

Metadata-only

Cancer risk and tumour spectrum in 172 patients with a germline SUFU pathogenic variation: a collaborative study of the SIOPE Host Genome Working Group

Guerrini-Rousseau, Léa Masliah-Planchon, Julien Waszak, Sebastian M

Background Little is known about risks associated with germline SUFU pathogenic variants (PVs) known as a cancer predisposition syndrome. Methods To study tumour risks, we have analysed data of a large cohort of 45 unpublished patients with a germline SUFU PV completed with 127 previously published patients. To reduce the ascertainment bias due...

Uploaded on: February 7, 2024
October 20, 2023 (v1)

Journal article

Metadata-only

Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups

Lobón-Iglesias, María-Jesús Andrianteranagna, Mamy Han, Zhi-Yan

Abstract Atypical teratoid rhabdoid tumors (ATRT) are divided into MYC, TYR and SHH subgroups, suggesting diverse lineages of origin. Here, we investigate the imaging of human ATRT at diagnosis and the precise anatomic origin of brain tumors in the Rosa26-Cre ERT2 ::Smarcb1 flox/flox model. This cross-species analysis points to an...

Uploaded on: November 25, 2023