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BROSSARD M

Last name: BROSSARD M

2013 (v1)

Publication

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Association of Genetic Variants in CDK6 and XRCC1 with the Risk of Dysplastic Nevi in Melanoma-Prone Families.

Liang X Pfeiffer RM Li WQ

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Uploaded on: April 14, 2023
2018 (v1)

Publication

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Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

Zhang, Tongwu Choi, Jiyeon Kovacs, Michael A.

Most expression quantitative trait locus (eQTL) studies to date have been performed in heterogeneous tissues as opposed to specific cell types. To better understand the cell-type-specific regulatory landscape of human melanocytes, which give rise to melanoma but account for <5% of typical human skin biopsies, we performed an eQTL analysis in...

Uploaded on: April 14, 2023
2018 (v1)

Publication

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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Duffy, David L Zhu, Gu Li, Xin

The total number of acquired melanocytic nevi on the skin is strongly correlated with melanoma risk. Here we report a meta-analysis of 11 nevus GWAS from Australia, Netherlands, UK, and USA comprising 52,506 individuals. We confirm known loci including MTAP, PLA2G6, and IRF4, and detect novel SNPs in KITLG and a region of 9q32. In a bivariate...

Uploaded on: April 14, 2023