CÁRCEL VALLE , Lucía

En esta tesis analizamos si la modulación de la actividad dopaminérgica producida por el haloperidol puede actuar como un estímulo incondicionado. La administración del fármaco provoca un efecto intenso sobre la actividad locomotora e induce catalepsia. Para confirmar si la administración repetida de 0.5 mg/kg de haloperidol en presencia de...

Repeated pairings of a neutral context and the effects of haloperidol give rise to conditioned catalepsy when the context is subsequently presented in a drug-free test. In order to confirm whether this response is based on Pavlovian processes, we conducted two experiments involving two manipulations that affect conditioning intensity in...

Dopamine antagonist drugs have profound effects on locomotor activity. In particular, the administration of the D2 antagonist haloperidol produces a state that is similar to catalepsy. In order to confirm whether the modulation of the dopaminergic activity produced by haloperidol was repeatedly paired with the presence of distinctive contextual...

Previous research has revealed a high degree of complexity of the conditioned response that appears after associating a context with the effects of the dopaminergic antagonist haloperidol. Specifically, when a drug-free test is performed in the presence of the context, conditioned catalepsy is observed. However, if the test is extended over...