CANZONIERI V.

Gastrointestinal stromal tumours (GIST) represent a rare borderline neoplastic disease, which is currently thought to arise from the interstitial cells of Cajal, very few cases of pancreatic GIST having been reported so far. We report a case of a 60 year-old man with an incidental imaging (MRI) finding of a solid mass in the pancreatic head,...

Context.-A significant negative trend in length of cone excision has been observed in recent years, leading to a higher percentage of positive endocervical excision margin and close (<1 mm) negative endocervical margin cases.Objective.-To evaluate the rate of disease persistence and recurrence after cervical excision for cervical...

Background: Small bowel adenocarcinoma is a relatively rare cancer, often diagnosed in an advanced stage. In localized and resectable disease, surgery alone or in combination with adjuvant chemotherapy is the mainstay of treatment. In the recently published National Comprehensive Cancer Network Clinical Practice guidelines, criteria for...

Small bowel adenocarcinomas (SBAs) are often associated with poor prognosis and have limited therapeutic options. Programmed cell death protein-1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway blockade is an effective treatment in many microsatellite instability-high (MSI-H) solid tumors. We aimed at investigating PD-L1 and PD-1...