Background and objectives: To evaluate the predictive value of serum neurofilament light chain (sNfL) and CSF NfL (cNfL) in patients with radiologically isolated syndrome (RIS) for evidence of disease activity (EDA) and clinical conversion (CC).Methods: sNfL and cNfL were measured at RIS diagnosis by single-molecule array (Simoa). The risk of...
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2022 (v1)Journal articleUploaded on: October 13, 2023
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August 2021 (v1)Journal article
BACKGROUND: Sex steroids could explain the course of multiple sclerosis (MS) in pregnancy. OBJECTIVE: To compare the annualized relapse rate (ARR) 12 weeks post-partum in women treated with nomegestrol acetate (NOMAc) and 17-beta-estradiol (E2) versus placebo. METHODS: POPARTMUS is a randomized, proof-of-concept trial in women with MS,...
Uploaded on: December 4, 2022