International audience
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February 7, 2011 (v1)Conference paperUploaded on: February 22, 2023
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February 7, 2011 (v1)Conference paper
International audience
Uploaded on: December 3, 2022 -
May 4, 2012 (v1)Report
The purpose of this work is to show how algebraic and symbolic techniques such as Smith normal forms and Gröbner basis techniques can be used to develop new Schwarz-like algorithms and preconditioners for linear systems of partial differential equations
Uploaded on: December 3, 2022 -
2013 (v1)Book section
Some algorithmic aspects of systems of PDEs based simulations can be better clarified by means of symbolic computation techniques. This is very important since numerical simulations heavily rely on solving systems of PDEs. For the large-scale problems we deal with in today's standard applications, it is necessary to rely on iterative Krylov...
Uploaded on: October 11, 2023 -
2013 (v1)Book section
Some algorithmic aspects of systems of PDEs based simulations can be better clarified by means of symbolic computation techniques. This is very important since numerical simulations heavily rely on solving systems of PDEs. For the large-scale problems we deal with in today's standard applications, it is necessary to rely on iterative Krylov...
Uploaded on: December 2, 2022 -
2012 (v1)Publication
Some algorithmic aspects of systems of PDEs based simulations can be better clarified by means of symbolic computation techniques. This is very important since numerical simulations heavily rely on solving systems of PDEs. For the large-scale problems we deal with in today's standard applications, it is necessary to rely on iterative Krylov...
Uploaded on: December 3, 2022 -
November 2011 (v1)Journal article
AXL is a receptor tyrosine kinase of the TAM family, the function of which is poorly understood. We previously identified AXL overexpression in Imatinib (IM)-resistant CML cell lines and patients. The present study was conducted to investigate the role of AXL and the mechanisms underlying AXL overexpression in Tyrosine Kinase Inhibitor...
Uploaded on: October 14, 2023 -
December 1, 2011 (v1)Journal article
Mitotic catastrophe (MC) is induced when stressed cells enter prematurely or inappropriately into mitosis and can be caused by ionizing radiation and anticancer drugs. Foretinib is a multikinase inhibitor whose mechanism of action is incompletely understood. We investigated here the effect of Foretinib on chronic myelogenous leukemia (CML) cell...
Uploaded on: December 2, 2022 -
December 31, 2022 (v1)Journal article
Macrophages are widely distributed innate immune cells that play an indispensable role in a variety of physiologic and pathologic processes, including organ development, host defense, acute and chronic inflammation, solid and hematopoietic cancers. Beyond their inextricable role as conveyors of programmed cell death, we have previously...
Uploaded on: February 22, 2023 -
April 2012 (v1)Journal article
Azacitidine is the leading compound to treat patients suffering myelodysplastic syndrome (MDS) or AML with less than 30% of blasts, but a majority of patients is primary refractory or rapidly relapses under treatment. These patients have a drastically reduced life expectancy as compared to sensitive patients. Therefore identifying predictive...
Uploaded on: October 14, 2023 -
November 15, 2022 (v1)Journal article
No description
Uploaded on: March 25, 2023 -
2019 (v1)Journal article
IntroductionCPX-351 is a liposomal formulation of cytarabine and daunorubicin packaged at a 5:1 molar ratio. This drug has recently been approved by FDA and EMEA for patients with therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (MRC-AML).The primary objective of this study was to analyze the efficacy of...
Uploaded on: December 3, 2022 -
March 2017 (v1)Journal article
60-70% of AML patients have an indication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) during their treatment. Graft versus host disease (GvHD), the major cause of mortality and comorbidities post-transplantation, develops by immunological mechanism and decides greatly prognosis and quality of life (QoL) of graft recipient....
Uploaded on: February 28, 2023 -
June 11, 2013 (v1)Journal articleMonosomal karyotype improves IPSS-R stratification in MDS and AML patients treated with Azacitidine.
IPSS-R classifies cytogenetic abnormalities into five prognostic groups for survival. Monosomal karyotype (MK) is not a subgroup of IPSS-R. Additional prognostic information from MK in poor and very poor karyotype has been recently shown. The aim of our study was to determine the prognostic value of IPSS-R and MK for response and survival in...
Uploaded on: December 4, 2022 -
2021 (v1)Journal article
CPX-351 is a liposomal formulation of cytarabine and daunorubicin approved for the treatment of adults with newly diagnosed, therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (MRC-AML). We retrospectively analyzed the efficacy and safety of CPX-351 in a real-world setting in 103 patients from 12 French...
Uploaded on: December 3, 2022 -
2018 (v1)Journal article
60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, DEC 01-04, 2018
Uploaded on: December 3, 2022 -
2020 (v1)Journal article
In this study, we aimed to refine prognostication of older with acute myeloid leukemia (AML) after intensive chemotherapy. Five hundred and nine patients aged 60 years or older (median age, 68 years) were prospectively enrolled in the intensive Acute Leukemia French Association (ALFA)-1200 trial between 2012 and 2016, and 471 patient samples...
Uploaded on: December 4, 2022