C

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CRISTOFERI , Laura

Last name: CRISTOFERI

First name: Laura

2018 (v1)

Publication

Metadata-only

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

Carbone, Marco Nardi, Alessandra Flack, Steve

Treatment guidelines recommend a stepwise approach to primary biliary cholangitis: all patients begin treatment with ursodeoxycholic acid (UDCA) monotherapy and those with an inadequate biochemical response after 12 months are subsequently considered for second-line therapies. However, as a result, patients at the highest risk can wait the...

Uploaded on: April 14, 2023
2022 (v1)

Publication

Metadata-only

Predictors of Serious Adverse Events and Non-response in Cirrhotic Patients With Primary Biliary Cholangitis treated with Obeticholic Acid

De Vincentis, Antonio D'Amato, Daphne Cristoferi, Laura

Obeticholic acid (OCA) has recently been restricted in patients with primary biliary cholangitis (PBC) with "advanced cirrhosis" because of its narrow therapeutic index. We aimed at better defining the predicting factors of hepatic serious adverse events (SAEs) and non-response in cirrhotic patients undergoing OCA therapy.

Uploaded on: February 14, 2024