DOLAN , Raymond J.

Background: Genetic risk is thought to drive clinical variation on a spectrum of schizophrenia-like traits, but the underlying changes in brain structure that mechanistically link genomic variation to schizotypal experience and behavior are unclear. Methods: We assessed schizotypy using a self-reported questionnaire and measured magnetization...

Decision-making is a cognitive process of central importance for the quality of our lives. Here, we ask whether a common factor underpins our diverse decision-making abilities. We obtained 32 decision-making measures from 830 young people and identified a common factor that we call ''decision acuity,'' which was distinct from IQ and reflected a...

A characteristic of adaptive behavior is its goal-directed nature. Anability to act in a goal-directed manner is progressively refinedduring development, but this refinement can be impacted by theemergence of psychiatric disorders. Disorders of compulsivity havebeen framed computationally as a deficit in model-based control,and have been linked...