DURAND , Matthieu

This paper investigates the use of constrained surrogate models to solve the multi-design optimization problem of a flexible hydrofoil. The surrogate-based optimization (EGO) substitutes the complex objective function of the problem by an easily evaluable model, constructed from a limited number of computations at carefully selected design...

In this work, we compare the use of Gaussian Process (GP) models for the constraints with a classification approach relying on a Least-Squares Support Vector Machine (LS-SVM). We propose several adaptations of the classification approach in order to improve the efficiency of the EGO procedure, in particular an extension of the binary LS-SVM...

International audience

Seven cases of translocation-associated renal cell carcinoma involving ALK (ALK-tRCC) were referenced in the last World Health Organization's classification (2016), in a group of emerging/provisional RCC. The first three cases were pediatric, medullary-based, associated with sickle cell trait and showed a fusion of ALK with VCL. Thirteen cases...

The accurate recognition of surgical instruments is essential for the advancement of intraoperative artificial intelligence (AI) systems. In this study, we assessed the YOLOv8 model's efficacy in identifying robotic and laparoscopic instruments in robot-assisted abdominal surgeries. Specifically, we evaluated its ability to detect, classify,...

Despite close follow-up of patients with native arteriovenous fistulas (AVFs), up to 10% experience thrombosis each year. The OSMOSIS Study (Osteopontin as a Marker of Stenosis) tested the hypothesis that the systemic osteopontin level, a pro-inflammatory mediator related to vascular remodelling and intimal hyperplasia, increases in AVF...

International audience

Objectives: To investigate the role of cancer-associated fibroblasts (CAFs) in clear cell renal cell carcinoma (ccRCC) with respect to tumour aggressiveness, metastasis development, and resistance to anti-angiogenic therapy (vascular endothelial growth factor receptor-tyrosine kinase inhibitors [VEGFR-TKI]).Patients and methods: Our study...

International audience

BACKGROUND: This national multicentre retrospective cohort study aimed to assess the long-term outcomes of dual kidney transplantation (DKT) and compare them with those obtained from single kidney transplantation (SKT). METHODS: Our first analysis concerned all first transplants performed between May 2002 and December 2014, from marginal...