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FONCK , Marianne

Last name: FONCK

First name: Marianne

January 5, 2010 (v1)

Journal article

Metadata-only

KRAS and BRAF Mutational Status in Primary Colorectal Tumors and Related Metastatic Sites: Biological and Clinical Implications.

Italiano, Antoine Hostein, Isabelle Soubeyran, Isabelle

BACKGROUND: KRAS and BRAF mutations in primary colorectal tumors (PT) are predictive of nonresponse to anti-epidermal growth factor receptor (EGFR) antibodies in patients with metastatic colorectal cancer (mCRC). The question of primary resistance to anti-EGFR treatment as a result of the presence of KRAS or BRAF mutations only in metastases...

Uploaded on: December 3, 2022
2021 (v1)

Journal article

Metadata-only

Clinical Relevance of Viable Circulating Tumor Cells in Patients with Metastatic Colorectal Cancer: The COLOSPOT Prospective Study

Mazard, Thibault Cayrefourcq, Laure Perriard, Françoise

Background: Circulating tumor cells (CTCs) allow the real-time monitoring of tumor course and treatment response. This prospective multicenter study evaluates and compares the early predictive value of CTC enumeration with EPISPOT, a functional assay that detects only viable CTCs, and with the CellSearch® system in patients with metastatic...

Uploaded on: December 3, 2022