Autophagy is a degradative conserved process in eukaryotes to recycle unwanted cellular protein aggregates and damaged organelles. Autophagy plays an important role under normal physiological conditions in multiple biological processes, but it is induced under cellular stress. Therefore, it needs to be tightly regulated to respond to different...
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February 21, 2022 (v1)PublicationUploaded on: March 25, 2023
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July 15, 2022 (v1)Publication
Hydrogen sulfide is a signalling molecule with a well-established impact on both plant and animal physiology. Intense investigation into the regulation of autophagy by sulfide in Arabidopsis thaliana has revealed that the post-translational modification of persulfidation/S-sulfhydration plays a key role. In this review focused on plants, we...
Uploaded on: March 25, 2023 -
March 21, 2019 (v1)Publication
The minor chloroplastic O-acetylserine(thiol)lyase isoform encoded by the CS26 gene in Arabidopsis thaliana has been described as an S-sulfocysteine synthase enzyme that plays an important role in chloroplast function. This enzyme is located in the thylakoid lumen, and its S-sulfocysteine activity is essential for the proper photosynthetic...
Uploaded on: March 27, 2023 -
January 29, 2018 (v1)Publication
In non-cyanogenic plants, cyanide is a co-product of ethylene and camalexin biosynthesis. To maintain cyanide at non-toxic levels, Arabidopsis plants express the mitochondrial β-cyanoalanine synthase CYS-C1. CYS-C1 knockout leads to an increased level of cyanide in the roots and leaves and a severe defect in root hair morphogenesis, suggesting...
Uploaded on: December 5, 2022 -
June 18, 2021 (v1)Publication
In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a...
Uploaded on: March 25, 2023 -
October 31, 2018 (v1)Publication
Hydrogen sulfide (H2S) has been largely referred as a toxic gas and environmental hazard, but recent years, it has emerged as an important gas-signaling molecule with effects on multiple physiological processes in both animal and plant systems. The regulatory functions of H2S in plants are involved in important processes such as the modulation...
Uploaded on: March 27, 2023 -
November 29, 2023 (v1)Publication
Planta resistente a medios con metales pesados. La presente invención se refiere a una planta con una elevada capacidad de acumular metales pesados en su parte aérea y su empleo en la recuperación de medios contaminados con metales pesados. Las plantas han sido modificadas genéticamente para ser resistentes a medios contaminados por metales...
Uploaded on: December 3, 2023 -
January 18, 2018 (v1)Publication
Hydrogen sulfide is a highly reactive molecule that is currently accepted as a signaling compound. This molecule is as important as carbon monoxide in mammals and hydrogen peroxide in plants, as well as nitric oxide in both eukaryotic systems. Although many studies have been conducted on the physiological effects of hydrogen sulfide, the...
Uploaded on: March 27, 2023 -
July 19, 2024 (v1)Publication
Hydrogen sulfide (H2S) is an endogenously generated gaseous signaling molecule, which recently has been implicated in autophagy regulation in both plants and mammals through persulfidation of specific targets. Persulfidation has been suggested as the molecular mechanism through which sulfide regulates autophagy in plant cells. ATG18a is a core...
Uploaded on: July 20, 2024 -
January 9, 2018 (v1)Publication
Accumulating experimental evidence in mammalian, and recently plant, systems has led to a change in our understanding of the role played by hydrogen sulfide in life processes. In plants, hydrogen sulfide mitigates stress and regulates important plant processes such as photosynthesis, stomatal movement, and autophagy, although the underlying...
Uploaded on: December 4, 2022 -
December 20, 2017 (v1)Publication
Hydrogen sulfide-mediated signaling pathways regulate many physiological and pathophysiological processes in mammalian and plant systems. The molecular mechanism by which hydrogen sulfide exerts its action involves the post-translational modification of cysteine residues to form a persulfidated thiol motif, a process called protein...
Uploaded on: March 27, 2023 -
September 15, 2020 (v1)Publication
Hydrogen sulfide (H2S) has always been considered toxic, but a huge number of articles published more recently showed the beneficial biochemical properties of its endogenous production throughout all regna. In this review, the participation of H2S in many physiological and pathological processes in animals is described, and its importance as a...
Uploaded on: December 5, 2022 -
March 20, 2019 (v1)Publication
In Arabidopsis thaliana, cyanide is produced concomitantly with ethylene biosynthesis and is mainly detoxified by the ß-cyanoalanine synthase CAS-C1. In roots, CAS-C1 activity is essential to maintain a low level of cyanide for proper root hair development. Root hair elongation relies on polarized cell expansion at the growing tip, and we have...
Uploaded on: March 27, 2023 -
March 6, 2018 (v1)Publication
In non-cyanogenic species, the main source of cyanide derives from ethylene and camalexin biosyntheses. In mitochondria, cyanide is a potent inhibitor of the cytochrome c oxidase and is metabolised by the β-Cyanoalanine synthase CYS-C1, catalysing the conversion of cysteine and cyanide to hydrogen sulfide and β- cyanoalanine. The hydrogen...
Uploaded on: March 27, 2023 -
January 30, 2018 (v1)Publication
Cyanide is produced concomitantly with ethylene biosynthesis. Arabidopsis (Arabidopsis thaliana) detoxifies cyanide primarily through the enzyme b-cyanoalanine synthase, mainly by the mitochondrial CYS-C1. CYS-C1 loss of function is not toxic for the plant and leads to an increased level of cyanide in cys-c1 mutants as well as a root hairless...
Uploaded on: December 5, 2022 -
November 30, 2023 (v1)Publication
Secuencias reguladoras de la expresión de genes en tricomas de plantas y sus aplicaciones. Se describen secuencias de nucleótidos que regulan la expresión de genes de interés en tricomas de plantas, construcciones y vectores que contienen dichas secuencias, y sus aplicaciones con fines biotecnológicos. De aplicación en Agricultura.
Uploaded on: December 3, 2023 -
February 27, 2024 (v1)Publication
Hydrogen sulfide (H2S) is a signaling molecule that regulates essential plant processes. In this study, the role of H2S during drought was analysed, focusing on the underlying mechanism. Pretreatments with H2S before imposing drought on plants substantially improved the characteristic stressed phenotypes under drought and decreased the levels...
Uploaded on: March 3, 2024 -
April 7, 2017 (v1)Publication
Hydrogen sulfide is an important signaling molecule that functions as a physiological gasotransmitter of comparable importance to NO and CO in mammalian systems. In plants, numerous studies have shown that sulfide increases tolerance/resistance to stress conditions and regulates essential processes. The endogenous production of hydrogen sulfide...
Uploaded on: December 4, 2022 -
July 19, 2017 (v1)Publication
Hydrogen sulfide is already recognized as an important signaling molecule in mammalian systems, and emerging data suggest that H2S is a signaling molecule just as important as nitric oxide (NO) and H2O2 in plants. Although sulfide is generated in chloroplasts and mitochondria, it is present predominantly in the charged HS- form due to the basic...
Uploaded on: December 4, 2022