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GRAFF , Caroline

Last name: GRAFF

First name: Caroline

2015 (v1)

Publication

Metadata-only

DNMT3A moderates cognitive decline in subjects with mild cognitive impairment: Replicated evidence from two mild cognitive impairment cohorts

Chouliaras, Leonidas Kenis, Gunter Visser, Pieter Jelle

Epigenetic dysregulation has been associated with cognitive decline and Alzheimer's disease. The present study investigated associations between common SNPs in genes regulating DNA methylation and age-related changes in cognitive decline in two independent prospective cohorts of patients suffering from mild cognitive impairment. An association...

Uploaded on: April 14, 2023
August 13, 2018 (v1)

Publication

Metadata-only

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: applied to GENFI study

Cury, Claire Durrleman, Stanley Cash, David M.

Brain atrophy as measured from structural MR images, is one of the primary imaging biomarkers used to track neurodegenerative disease progression. In diseases such as frontotemporal dementia or Alzheimer's disease, atrophy can be observed in key brain structures years before any clinical symptoms are present. Atrophy is most commonly captured...

Uploaded on: December 4, 2022