HACHFI , Salma

The Bacillus Cereus (B cereus) group consists of Gram-positive bacteria, commonly isolated from the environment. Members of the B. cereus group are spore-forming bacteria commonly associated with food poisoning and intestinal infections and represent the third cause of food poisoning in Europe and the second in France. The most-studied members...

The intestine is endowed with an innate immune system that is required to fight any exogenous bacteria that are swallowed along with the food. The first line of defense that is mounted by the gut epithelium is the release of immune Reactive Oxygen Species (ROS), such as hypochlorous acid (HOCl), into the lumen. HOCl is produced within 1.5 h of...

Members of the Bacillus cereus group are spore-forming bacteria commonly associated with foodborne outbreaks. The capacity of these bacteria to form highly resistant dormant entities, called spores, enables them to survive under extreme conditions. Bacillus thuringiensis (Bt) belongs to the group of B. cereus. Thanks to the toxins (named Cry)...

SUMMARY Spores are considered as dormant entities highly resistant to extreme conditions. Among them, Bacillus cereus spores are commonly associated with foodborne outbreaks. Nevertheless, the pathological processes associated with spore ingestion and germination remain poorly understood. Here, we show that while ingestion of vegetative...

International audience

Strains of the Bacillus cereus (Bc) group are sporulating bacteria commonly associated with foodborne outbreaks. Spores are dormant cells highly resistant to extreme conditions. Nevertheless, the pathological processes associated with the ingestion of either vegetative cells or spores remain poorly understood. Here, we demonstrate that while...

Strains of the Bacillus cereus (Bc) group are sporulating bacteria commonlyassociated with foodborne outbreaks. Spores are dormant cells highly resistantto extreme conditions. Nevertheless, the pathological processes associatedwith the ingestion of either vegetative cells or spores remain poorlyunderstood. Here, we demonstrate that while...