A significant number of surgical patients are at risk of intra- or post-operative complications or both, which are associated with increased lengths of stay, costs, and mortality. Reducing these risks is important for the individual patient but also for health-care planners and managers. Insufficient tissue perfusion and cellular oxygenation...
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2015 (v1)PublicationUploaded on: April 14, 2023
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January 1, 2019 (v1)Journal article
After the attacks in Paris, France was again struck by terrorism in the city of Nice during the night of July 14, 2016. At 22:33 in the evening, a 19-ton truck drove into the crowd of holiday celebrators. The attack resulted in 458 wounded and 86 deaths. The purpose of this study was to describe the management of patients with abdominal trauma...
Uploaded on: December 4, 2022 -
2017 (v1)Publication
Purpose: We assessed outcomes in brain-injured patients after implementation of a multi-faceted approach to reduce respiratory complications in intensive care units. Methods: Prospective nationwide before–after trial. Consecutive adults with acute brain injury requiring mechanical ventilation for ≥24 h in 20 French intensive care units (ICUs)...
Uploaded on: April 14, 2023 -
December 2018 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
January 1, 2018 (v1)Journal article
Existing methods to predict recovery after out-of-hospital cardiac arrest (OHCA) lack of accuracy. The aim of this study was to determine whether quantitative proton chemical shift imaging (1H-CSI) during the subacute stage of OHCA can predict neurological outcome of such patients. This monocentric prospective observational study was conducted...
Uploaded on: December 4, 2022 -
August 2013 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
February 28, 2021 (v1)Journal article
Background: Excess visceral fat (VF) or high body mass index (BMI) is risk factors for severe COVID-19. The receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is expressed at higher levels in the VF than in the subcutaneous fat (SCF) of obese patients.Aim: To show that visceral fat accumulation better predicts severity of...
Uploaded on: December 3, 2022 -
September 1, 2014 (v1)Journal article
Introduction: Hyperglycemia is a marker of poor prognosis in severe brain injuries. There is currently little dataregarding the effects of intensive insulin therapy (IIT) on neurological recovery.Methods: A sub-group analysis of the randomized-controlled CGAO-REA study (NCT01002482) in surgical intensivecare units (ICU) of two university...
Uploaded on: March 25, 2023 -
2014 (v1)Journal article
IntroductionHyperglycemia is a marker of poor prognosis in severe brain injuries. There is currently little data regarding the effects of intensive insulin therapy (IIT) on neurological recovery.MethodsA sub-group analysis of the randomized-controlled CGAO-REA study (NCT01002482) in surgical intensive care units (ICU) of two university...
Uploaded on: February 28, 2023 -
2017 (v1)Journal article
Ambulatory surgery can be carried out on a diabetic patient. By using a close organisational and technical approach, it minimises the risk of disequilibrium and allows the patient to return to his (her) previous way of life more quickly. Taking into account the context of this surgery with return home the same day, the objectives are to...
Uploaded on: September 5, 2023 -
2017 (v1)Journal article
Diabetes mellitus consists of a chronic elevation of blood sugar levels linked to insulin resistance and/or insulinopenia. Its diagnosis is based on a fasting blood glucose level of ≥ 1.26 g/L or, in some countries, a blood glycated haemoglobin (HbA1c) level of > 6.5%. There are several forms of diabetes. Type 2 diabetes (T2D) is the most...
Uploaded on: September 5, 2023 -
2017 (v1)Journal article
Transition from continuous intravenous insulin infusion administered intraoperatively is an important element in the postoperative management of a diabetic patient. The basal-bolus scheme is the most suitable strategy taking into account the nutritional supply and variable needs for insulin. It reproduces the physiology of a normal pancreas:...
Uploaded on: September 5, 2023 -
2017 (v1)Journal article
It is necessary to refer a patient to a diabetologist perioperatively in several circumstances. Preoperatively, the patient is referred if diabetes is discovered or if glycaemic disequilibrium is detected (HbA 1c < 5% or > 8%). During the hospital stay, a diabetologist should be consulted if diabetes is discovered, if there is glycaemic...
Uploaded on: September 5, 2023 -
2017 (v1)Journal article
In diabetic patients undergoing surgery, it is necessary to evaluate how well glycaemic levels are controlled preoperatively. This evaluation assesses glycated haemoglobin (HbA1c) levels and recent capillary blood sugar levels. Treatment adaptation may be necessary before surgery The specific complications of diabetes should be investigated....
Uploaded on: September 5, 2023 -
2017 (v1)Journal article
International audience
Uploaded on: September 5, 2023 -
2017 (v1)Journal article
Perioperative hyperglycemia (> 1.80 g/L or 10 mmol/L) is associated with increased morbidity (particularly infection) and mortality. It is managed by decreasing blood sugar levels with insulin. Control of blood sugar levels between 0.90 and 1.80 g/L (5–10 mmol/L) helps to avoid hypoglycemia, which is more frequent when strict normoglycemia is...
Uploaded on: September 5, 2023 -
December 2017 (v1)Journal article
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Uploaded on: December 4, 2022 -
2018 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
2015 (v1)Journal article
Introduction Using a randomized controlled trial comparing tight glucose control with a computerized decision-support systems and conventional protocols (post hoc analysis), we tested the hypothesis that hypoglycemia is associated with a poor outcome, even when controlling for initial severity. Methods We looked for moderate (2.2-3.3mmol/l) and...
Uploaded on: March 25, 2023 -
2018 (v1)Journal article
OBJECTIVES:Acute kidney injury requiring renal replacement therapy is a major concern in ICUs. Initial renal replacement therapy modality, continuous renal replacement therapy or intermittent hemodialysis, may impact renal recovery. The aim of this study was to assess the influence of initial renal replacement therapy modality on renal recovery...
Uploaded on: December 4, 2022 -
November 3, 2020 (v1)Journal article
BackgroundRecent literature reports a strong thrombotic tendency in patients hospitalized for a coronavirus disease 2019 (COVID‐19) infection. This characteristic is unusual and seems specific to COVID‐19 infections, especially in their severe form. Viral infections can trigger acquired thrombophilia, which can then lead to thrombotic...
Uploaded on: December 4, 2022 -
December 2018 (v1)Journal article
International audience
Uploaded on: December 4, 2022