LE GALL , Pascale

In this paper we present meta-rules to express an infinite class of semantically related graph transformation rules in the context of pure topological modelling with G-maps. Our proposal is motivated by the need of describing specific operations to be done on topological representations of ob jects in computer graphics, especially for...

In the course of understanding biological regulatory networks (BRN), scientists usually start by studying small BRNs that they believe to be of particular importance to represent a biological function, and then, embed them in a larger network. Such a reduction can lead to neglect relevant regulations and to study a network whose properties can...

Many complex cellular processes involve major changes in topology and geometry. We have developed a method using topology-based geometric modelling in which the edge labels of an n-dimensional generalized map (a sub-class of graphs) represent the relations between neighbouring biological compartments. We illustrate our method using two...

The Golgi apparatus is the place in the cell where proteins re main for a maturation phase before their excretion. Several hypotheses on its dynamics have been formulated under the form of schematic models. The GolgiTop working group initiated by the Epigenomics Project (Genopole, Evry) aims at studying the 3-dimensional structure and dynamics...