Although the use of corticosteroids in juvenile idiopathic arthritis (JIA) is now much more limited owing to the availability of methotrexate and biological agents, there are clinical scenarios where it is still indicated. For example, corticosteroids may be indicated for intraarticular injections to prevent joint deformities, as a "bridge"...
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2014 (v1)PublicationUploaded on: April 14, 2023
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2016 (v1)Publication
Juvenile idiopathic arthritis (JIA) is a heterogeneous group of arthritides characterized by chronic synovial inflammation that can lead to structural damage. The main objective of JIA therapies is to induce disease control to avoid disability in childhood. The advances in therapeutic effectiveness have created a need to search for imaging...
Uploaded on: April 14, 2023 -
2013 (v1)Publication
Paediatric-onset systemic lupus erythematosus (SLE) is usually more severe than its adult counterpart. In particular, there is a higher incidence of renal and central nervous system involvement. Specific measures to assess disease activity and damage have been implemented. The disease is very rare before the fifth birthday and therefore the...
Uploaded on: April 14, 2023 -
2014 (v1)Publication
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Uploaded on: April 14, 2023 -
2010 (v1)Publication
Abstract Juvenile idiopathic arthritis (JIA) represents a group of heterogeneous diseases characterized by a chronic inflammatory process primarily targeting the synovial membrane. A persistent synovitis is associated with an increased risk of osteocartilaginous damage.With the advent of effective structure-modifying treatment for JIA, it may...
Uploaded on: May 11, 2023 -
2011 (v1)Publication
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Uploaded on: April 14, 2023 -
2012 (v1)Publication
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Uploaded on: May 11, 2023 -
2007 (v1)Publication
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Uploaded on: April 14, 2023 -
2013 (v1)Publication
Background: Novel autoantibodies targeting intracellular proteins are recently detected in patients with idiopathic inflammatory myopathies (IIMs). Objective. To evaluate the prevalence of these myositis-specific antibodies (MSAs) in juvenile IIMs (JIIMs) and their association with clinical characteristics and disease course. Methods: A...
Uploaded on: April 14, 2023 -
2011 (v1)Publication
US is a technique particularly suited to the investigation of musculoskeletal disorders in children and adolescents. This review paper describes a range of clinical settings beyond the hip joint where US has a significant role to play, including sports injuries, infectious diseases, inflammatory and degenerative conditions, congenital and...
Uploaded on: April 14, 2023 -
2001 (v1)Publication
Macrophage activation syndrome (MAS) is a potentially life threatening complication of chronic rheumatic diseases, particularly systemic juvenile idiopathic arthritis (JIA). A number of triggers have been related to the development of MAS, including viral infections, nonsteroidal antiinflammatory drug therapy, and gold salt injections. We...
Uploaded on: March 31, 2023 -
2001 (v1)Publication
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Uploaded on: March 27, 2023 -
2016 (v1)Publication
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Uploaded on: April 14, 2023 -
2008 (v1)Publication
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Uploaded on: May 13, 2023