MASSOBRIO , Paolo

In the latest years, several attempts to develop extracellular microtransducers to record electrophysiological activity of excitable cells have been done. In particular, many efforts have been oriented to increase the coupling conditions, and, thus, improving the quality of the recorded signal. Gold mushroom-shaped microelectrodes (GMμE) are an...

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We implemented an automated and efficient open-source software for the analysis of multi-site neuronal spike signals. The software package, named SpiCoDyn, has been developed as a standalone windows GUI application, using C# programming language with Microsoft Visual Studio based on .NET framework 4.5 development environment. Accepted input...

Functional-effective connectivity and network topology are nowadays key issues for studying brain physiological functions and pathologies. Inferring neuronal connectivity from electrophysiological recordings presents open challenges and unsolved problems. In this work, we present a cross-correlation based method for reliably estimating not only...

Thanks to recent improvements in the neurotechnology, parallel recordings with an ever-increasing number of micro-transducers are now available to monitor the neuronal spiking activity CP of large-scale neuronal networks. At the same time, continuous improvements are required to develop computationally efficient software for processing and...