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MOGHA , Ariane

Last name: MOGHA

First name: Ariane

2012 (v1)

Journal article

Metadata-only

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion

Fenouille, Nina Tichet, Mélanie Dufies, Maeva

During progression of melanoma, malignant melanocytes can be reprogrammed into mesenchymal-like cells through a process similar to epithelial-mesenchymal transition (EMT), which is associated with downregulation of the junctional protein E-cadherin and acquisition of a migratory phenotype. Recent evidence supports a role for SLUG, a...

Uploaded on: March 25, 2023
October 9, 2017 (v1)

Journal article

Metadata-only

A non-coding function of TYRP1 mRNA promotes melanoma growth

Gilot, David Migault, Mélodie Bachelot, Laura

Competition among RNAs to bind miRNA is proposed to influence biological systems. However, the role of this competition in disease onset is unclear. Here, we report that TYRP1 mRNA, in addition to encoding tyrosinase-related protein 1 (TYRP1), indirectly promotes cell proliferation by sequestering miR-16 on non-canonical miRNA response...

Uploaded on: February 28, 2023