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August 24, 2016 (v1)PublicationUploaded on: March 25, 2023
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November 3, 2022 (v1)Publication
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Uploaded on: March 24, 2023 -
September 13, 2021 (v1)Publication
Grape seed extract has demonstrated many activities in disease prevention, such as antioxidant effects, which make it a potential source of nutraceuticals. Grape seed is a remarkable winery industry by-product due to the bioactivity of its constituents. Methods for recovery of oil from grape seeds have evolved to improve both the quantity and...
Uploaded on: December 4, 2022 -
September 13, 2021 (v1)Publication
Pectins are a component of the complex heteropolysaccharide mixture present in the cell wall of higher plants. Structurally, the pectin backbone includes galacturonic acid to which neutral sugars are attached, resulting in functional regions in which the esterification of residues is crucial. Pectins influence many physiological processes in...
Uploaded on: March 25, 2023 -
May 29, 2023 (v1)Publication
effects on our health. Regarding cardiovascular disease, research needs to consider the amount consumed but also drinking thresholds, frequency of drinking, age and gender of consumers, lifestyle, or non-alcoholic com ponents of beers. Nevertheless, epidemiological evidence points to healthy effects of low or moderate beer consumption and...
Uploaded on: May 31, 2023 -
September 28, 2023 (v1)Publication
The immune-inflammatory, glucose homeostasis, and antioxidant response have a crucial role in the prevention of non-communicable chronic diseases, according to the World Health Organization (WHO). As people live longer in society, the lifestyle of human changes and the prevalence of age-related degenerative diseases and obesity is...
Uploaded on: October 11, 2023 -
September 24, 2021 (v1)Publication
Pectins comprise complex polysaccharides rich in galacturonic acid, that exert many functions in higher plants as components of the cell walls, together with cellulose or lignin. The food industry has traditionally used pectins as an additive due to their gelling or thickening properties. Pharmaceutical research is also taking advantage of...
Uploaded on: March 25, 2023 -
June 23, 2023 (v1)Publication
Alzheimer's disease (AD) is the most common form of dementia. The physiopathology of AD is well described by the presence of two neuropathological features: amyloid plaques and tau neurofibrillary tangles. In the last decade, neuroinflammation and cellular stress have gained importance as key factors in the development and pathology of AD....
Uploaded on: June 24, 2023 -
February 20, 2024 (v1)Publication
Malnutrition refers to a person's status as under- or overnourished, and it is usually associated with an inflammation status, which can subsequently imply a different health status, as the risk of infection is increased, along with a deterioration of the immune system. Children's immune systems are generally more susceptible to problems than...
Uploaded on: February 23, 2024 -
January 27, 2022 (v1)Publication
High-density lipoproteins (HDLs) are heterogeneous lipoproteins that modify their composition and functionality depending on physiological or pathological conditions. The main roles of HDL are cholesterol efflux, and anti-inflammatory and antioxidant functions. These functions can be compromised under pathological conditions. HDLs play a role...
Uploaded on: March 27, 2023 -
March 15, 2022 (v1)Publication
The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous pathological conditions. Exaggerated and prolonged states of postprandial hypertriglyceridemia are frequently related to the ingestion of meals enriched in saturated fatty acids (SFAs). MicroRNAs are noncoding RNAs that...
Uploaded on: December 4, 2022 -
April 14, 2023 (v1)Publication
Background: New challenges in our society are appearing following the emergence of antibiotic-resistant mi- croorganisms and the concerns about the use of antibiotics. Furthermore, food spoilage due to microorganisms leads to food waste of around 1.3 billion tons each year. Bioactive peptides obtained from food proteins, released by enzymatic...
Uploaded on: April 15, 2023 -
May 6, 2020 (v1)Publication
Evening primrose oil (EPO) is widely used as a dietary supplement from which beneficial effects have been reported in rheumatic and arthritic conditions, atopic dermatitis, psoriasis, premenstrual and menopausal syndrome, and diabetic neuropathy. The aim of this study was to determine whether phytosterols isolated from evening primrose oil...
Uploaded on: December 4, 2022 -
January 18, 2024 (v1)Publication
Hempseed (Cannabis sativa L.) has beneficial impact on human health mainly because of its wide variability of bioactive compounds. However, many of them are not fully characterized yet. In this work, hempseed was defatted and through a bio-guided studied, two fractions (F03 and F05) with the highest content of phenols, flavonoids and...
Uploaded on: January 20, 2024 -
February 12, 2024 (v1)Publication
The incorporation of novel, functional, and sustainable foods in human diets is increasing because of their beneficial effects and environmental-friendly nature. Chia (Salvia hispanica L.) has proved to be a suitable source of bioactive peptides via enzymatic hydrolysis. These peptides could be responsible for modulating several physiological...
Uploaded on: February 14, 2024 -
December 4, 2020 (v1)Publication
Wine production is an ancient human activity that generates several by-products, which include some constituents known for their potential in health care and for their role in the food or cosmetic industries. Any variety of grape (Vitis vinifera L.) contains nutrients and bioactive compounds available from their juice or solid parts. Grape seed...
Uploaded on: March 25, 2023 -
February 21, 2024 (v1)Publication
The immune system is somehow related to all the metabolic pathways, in a bidirectional way, and the nutritional interventions affecting these pathways might have a relevant impact on the inflammatory status of the individuals. Food-derived peptides have been demonstrated to exert several bioactivities by in vitro or animal studies. Their...
Uploaded on: February 23, 2024 -
May 6, 2020 (v1)Publication
Background: Through this work we evaluated the potential of the aqueous extract of Annona muricata L. leaves (AMAEL) to treat inflammatory conditions. The use of decoction or infusion of this important medicinal resource is still not scientifically validated. Methods: Different doses of AMAEL were assayed in carrageenan-induced inflammation and...
Uploaded on: December 5, 2022 -
March 15, 2022 (v1)Publication
Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that squalene has antioxidant, cardioprotective and anti-carcinogenic activities. Nevertheless, its anti-inflammatory properties remain unclear. The effects of squalene on lipopolysaccharide (LPS)-mediated inflammatory response in...
Uploaded on: March 25, 2023 -
March 9, 2022 (v1)Publication
Metabolic syndrome (MetS) is associated with obesity, dyslipemia, type 2 diabetes and chronic low-grade inflammation. The aim of this study was to determine the role of high-fat low-cholesterol diets (HFLCDs) rich in SFAs (HFLCD-SFAs), MUFAs (HFLCD-MUFAs) or MUFAs plus omega-3 long-chain PUFAs (HFLCD-PUFAs) on polarisation and inflammatory...
Uploaded on: March 25, 2023 -
March 14, 2022 (v1)Publication
We aimed to investigate the impact of high-fat low-cholesterol diets rich in saturated fatty acids (HFLCD-SFAs), monounsaturated FAs (HFLCD-MUFAs) or MUFAs + omega-3 long-chain polyunsaturated FAs (HFLCD-PUFAs) in combination with niacin (NA) on atherosclerotic plaque characteristics in a mouse model (Lepob/obLDLR−/−) of metabolic syndrome...
Uploaded on: March 25, 2023 -
March 9, 2022 (v1)Publication
Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in health status, as measured by reduced mortality from several chronic diseases. The current pandemic of obesity, metabolic syndrome, and type 2 diabetes is intimately associated with an atherogenic dyslipidemic phenotype. The...
Uploaded on: March 25, 2023