MUÑOZ DELGADO , Laura

Los mecanismos fisiopatológicos implicados de la enfermedad de Parkinson (EP) no se conocen por completo, pero la evidencia actual apoya la implicación de la respuesta inmune periférica y la inflamación en el inicio y la progresión de la enfermedad. Desentrañar los mecanismos patogénicos subyacentes en la neurodegeneración tiene un potencial...

Background: Hyperhomocysteinemia is considered an independent risk factor for cognitive impairment. Objective: To study the correlation between homocysteine levels and cognitive impairment in patients with PD. Methods: We conducted a case–control study that included 246 patients with PD, of whom 32 were cognitively impaired. The levels of...

Parkinson's disease (PD) is associated with an increasedstroke risk, however, no relationship between coronary arterydisease (CAD) and PD was found.1To date, little is knownabout the influence of PD-related genes, such as the leucine-rich repeat kinase 2 (LRRK2), the parkin (PRKN) and theglucocerebrosidase (GBA) genes, in the vascular risk of...