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PALADINO , Noemi

Last name: PALADINO

First name: Noemi

2022 (v1)

Publication

Metadata-only

Spontaneous NLRP3 inflammasome-driven IL-1-β secretion is induced in severe COVID-19 patients and responds to anakinra treatment

Bertoni, Arinna Penco, Federica Mollica, Hilaria

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may result in a severe pneumonia associated with elevation of blood inflammatory parameters, reminiscent of cytokine storm syndrome. Steroidal anti-inflammatory therapies have shown efficacy in reducing mortality in critically ill patients; however, the mechanisms by which...

Uploaded on: February 7, 2024