Background: The small-airway dysfunction (SAD), detected with impulse oscillometry (IOS) methods, has been recently better characterized in patients with asthma. However, little is known about SAD in asthmatic patients with normal spirometry (NS).Objective: In this study, we aimed to investigate, in an unselected sample of 321 patients with...
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2023 (v1)PublicationUploaded on: February 4, 2024
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2020 (v1)Publication
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Uploaded on: April 14, 2023 -
2022 (v1)Publication
Background: The identification of type-2 inflammation in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) acquires a crucial role in the endotypization needed for selecting patients for biological drugs targeting type-2 inflammation: to date, the parameters used include systemic and histological biomarkers. The aim of this study...
Uploaded on: February 14, 2024 -
2023 (v1)Publication
: The efficacy mepolizumab in severe asthmatic patients is proven in the literature. Primarily to study the effect of mepolizumab on exacerbations, steroid dependence, and the continuation of efficacy in the long term. Secondarily to evaluate the effect of the drug on nasal polyps. Analyzing data from SANI (Severe Asthma Network Italy) clinics,...
Uploaded on: February 14, 2024