RIBOT , Magali

Nous nous intéressons dans ce mémoire d'habilitation à diriger les recherches à l'étude de systèmes d'équations aux dérivées partielles afin de modéliser des phénomènes biologiques. Dans la première partie, nous étudions différents systèmes de type hyperbolique pour modéliser le phénomène de chimiotactisme, en s'intéressant particulièrement...

International audience

International audience

We introduce a new class of finite difference schemes for approximating the solutions to an initial-boundary value problem on a bounded interval for a one dimensional dissipative hyperbolic system with an external source term, which arises as a simple model of chemotaxis. Since the solutions to this problem may converge to non constant...

We consider two models which were both designed to describe the movement of eukaryotic cells responding to chemical signals. Besides a common standard parabolic equation for the diffusion of a chemoattractant, like chemokines or growth factors, the two models differ for the equations describing the movement of cells. The first model is based on...

In this paper we deal with a semilinear hyperbolic chemotaxis model in one space dimension evolving on a network, with suitable transmission conditions at nodes. This framework is motivated by tissue-engineering scaffolds used for improving wound healing. We introduce a numerical scheme, which guarantees global mass densities conservation....

We consider two models which were both designed to describe the movement of eukaryotic cells responding to chemical signals. Besides a common standard parabolic equation for the diffusion of a chemoattractant, like chemokines or growth factors, the two models differ for the equations describing the movement of cells. The first model is based on...

We present in this paper a spatial model describing the growth of a photosynthetic microalgae biofilm. In this model we consider photosynthesis, extracellular matrix excretion, and mortality. These mechanisms are described precisely using kinetic laws that take into account some saturation effects which limit the reaction rates and involve...

In this article, we study a one-dimensional hyperbolic quasi-linear model of chemotaxis with a non-linear pressure and we consider its stationary solutions, in particular with vacuum regions. We study both cases of the system set on the whole line $\Er$ and on a bounded interval with no-flux boundary conditions. In the case of the whole line...

We introduce a numerical scheme to approximate a quasi-linear hyperbolic system which models the movement of cells under the influence of chemotaxis. Since we expect to find solutions which contain vacuum parts, we propose an upwinding scheme which handles properly the presence of vacuum and, besides, which gives a good approximation of the...

We discuss the modelling of interacting populations through pursuit-evasion ---- or attraction-repulsion ---- principles~: preys try to escape chasers, chasers are attracted by the presence of preys. We construct a hierarchy of models, ranging from ODEs systems with finite numbers of individuals of each population, to hydrodynamic systems....

We discuss numerical strategies to deal with PDE systems describing traffic flows, taking into account a density threshold, which restricts the vehicles density in the situation of congestion. These models are obtained through asymptotic arguments. Hence, we are interested in the simulation of approached models that contain stiff terms and...

In this article, we study in details the fluid dynamics system proposed in Clarelli et al (2013) to model the formation of cyanobacteria biofilms. After analyzing the linear stability of the unique non trivial equilibrium of the system, we introduce in the model the influence of light and temperature, which are two important factors for the...

A system of nonlinear hyperbolic partial differential equations is derived using mixture theory to model the formation of biofilms. In contrast with most of the existing models, our equations have a finite speed of propagation, without using artificial free boundary conditions. Adapted numerical scheme will be described in detail and several...

We present a spatial model describing the growth of a photosynthetic microalgae biofilm. In this 2D-model we consider photosynthesis, cell carbon accumulation, extracellular matrix excretion, and mortality. The rate of each of these mechanisms is given by kinetic laws regulated by light, nitrate, oxygen and inorganic carbon. The model is based...

The gut microbiota, mainly located in the colon, is engaged in a complex dialogue with the large intestinal epithelium through which important regulatory processes for the health and well-being of the host take place. Imbalances of the microbial populations, called dysbiosis, are related to several pathological status, emphasizing the...

We propose in this article a model describing the dynamic of a system of adipocytes, struc-tured by their sizes. This model takes into account the differentiation of a population of mesenchymal cells into preadipocytes and of preadipocytes into adipocytes; the differentiation rates depend on the mean adipocyte radius. The considered equations...

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We introduce a mixture model intended to describe the dynamics of the mucus layer that wraps the gut mucosa. This model takes into account the fluid mechanics of the gut content, the inhomogeneous rheology that depends on the fluid composition, and the main physiological mechanisms that ensure the homoeostasis of the mucus layer. Numerical...