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2017 (v1)PublicationUploaded on: April 14, 2023
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2017 (v1)Publication
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2021 (v1)Publication
3-Hydroxyisoquinolines (ISOs) and their tautomeric isoquinolin-3-ones are heterocycles with attractive biological properties. Here we reported the revisited synthesis of a highly functionalized ISO that showed blue fluorescence and the characterization of its biological properties in an invertebrate animal model, the ascidian Ciona...
Uploaded on: April 14, 2023 -
2019 (v1)Publication
This chapter illustrates a series of recent examples on the cooperation of multicomponent reactions with biocatalysis and/or with the use of renewable starting materials derived from biomass. Teaming these three green methodologies affords important benefits from the point of view of sustainable synthesis. In particular, biocatalysts have been...
Uploaded on: April 14, 2023 -
2021 (v1)Publication
This perspective aims at celebrating the 100th anniversary of the discovery of the Passerini three component reaction. After being nearly neglected for many years, now this reaction has become quite popular, thanks to the achievements of the last 30 years, which have revealed several chances of exploitation in organic synthesis. Though not...
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2019 (v1)Publication
A photoinduced reaction between diazoketones, isocyanides and silanols, followed by aldol dimerization of the resulting multicomponent adduct, affords polyfunctionalized 3,5-dihydroxypyrrolidin-2-one heterocycles in a straightforward manner. Six new bonds and two quaternary carbons are formed in just two steps with this complexity-generating...
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2020 (v1)Publication
The search for new fluorescent molecules for possible applications as functional π-electron systems and their conjugation with different nanomaterials is nowadays of paramount importance to broaden the availability of materials with different properties. Herein we present a diversity-oriented approach to heterocyclic luminophores based on a...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
A chiral bio-based building block, prepared by the lipase-mediated desymmetrization of an erythritol derivative, was further functionalized and then submitted to stereoselective Passerini reactions, allowing the synthesis of a small library of new molecules. Thanks to the presence of different functional groups, further cyclizations were...
Uploaded on: April 14, 2023