SIMONACCI , Francesco

We conducted a randomized, prospective pilot study to evaluate the therapeutic effects (in particular, wound healing rate and pain relief) of one device that administers topical millimeter waves (MW) in patients with chronic skin ulcers of the lower extremities. Twenty consecutive patients with chronic skin ulcers of the lower extremities were...

The massive weight loss often resulted in an excess of loose skin mainly in the abdomen, upper arms, thighs, chest, back, and laterally on the back. Consequently, most patients sought for a solution, provided by the plastic surgery through the body-contouring surgery. Abdominoplasty, arm lift, tight lift, breast lift, and liposuction are all...

Oxidative stress is hypothesized to be one of the main causes of the pathophysiologic alterations observed during impaired healing of wounds. In the present study, we aimed to measure systemic levels of free radicals in blood and anti-oxidant (AO) activity in the plasma of patients with chronic ulcers (venous stasis ulcers and arterial...

LIPECTO MY AS A SOURCE OF STEM CELLS Over the last few years, interest in adipose tissue as the ideal source of mesenchymal stem cells (MSCs) has considerably grown. MSCs represent the future of regenerative medicine, both for their multipotent capabilities and for their ability to excretion of pro-regenerative cytokines. Mesenchymal stem cells...

Adipose tissue is an organ of energy storage, an endocrine organ, a soft tissue filler and a cosmetically unnecessary tissue discarded by liposuction. Liposuction was designed to correct unaesthetic deposits of subcutaneous fat; it produces satisfactory silhouette contouring when performed by appropriately trained operators using properly...

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Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, with an excellent prognosis after surgical removal. However, nodal metastasis are present in about 5% of cases and the death rate is about 2%.

Breast cancer is the most common noncutaneous malignancy among women worldwide. After a breast cancer removal procedure, women are asked to decide about breast reconstruction, mainly to improve their life quality, and they can choose from among many options. Broadly, there are two different types of breast reconstruction procedures: prosthetic...

Therapeutic approaches based on stem cells have recently been introduced to treat chronic ulcers, with good results. The aim of this study was to evaluate whether the topical application of adipose-derived stem cells (ASCs) with platelet-rich plasma (PRP) for the treatment of ischemic cutaneous ulcers modified the skin perfusion of the treated...

AIM: Basal Cell Carcinoma (BCC) alone accounts for 80% of cases of non-melanoma skin cancer (NMSC), which characteristically develops on sun-exposed skin. Indeed the most common site of BCC is the head and neck region (80%). The purpose of this study to review the experience of our center with BCC in the head and neck region to report the sites...

Background: Breast cancer is the leading cause of death attributable to cancer among women worldwide. Breast reconstruction has become an integrated part of breast cancer treatment due to long-term psychosexual health factors and its importance to breast cancer survivors. Muscle-sparing techniques using an acellular dermal matrix (ADM) (Braxon;...