The advent of dose intensified interval compressed therapy has improved event-free survival for patients with localized Ewing sarcoma (EwS) to 78% at 5 years. However, nearly a quarter of patients with localized tumors and 60–80% of patients with metastatic tumors suffer relapse and die of disease. In addition, those who survive are often left...
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May 30, 2023 (v1)PublicationUploaded on: May 31, 2023
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October 20, 2023 (v1)Journal article
Abstract Atypical teratoid rhabdoid tumors (ATRT) are divided into MYC, TYR and SHH subgroups, suggesting diverse lineages of origin. Here, we investigate the imaging of human ATRT at diagnosis and the precise anatomic origin of brain tumors in the Rosa26-Cre ERT2 ::Smarcb1 flox/flox model. This cross-species analysis points to an...
Uploaded on: November 25, 2023